Kidney Stone Surgical Procedures - New Gout Drugs - Pegloticase Continues Its Hopeful PathMay 2008 the U.S. based company developing Pegloticase made another upbeat statement assessment of what they have learnt in its Phase 3 and open label extension trials. Note that Pegloticase still awaits approval from medical authorities so I am writing here about a new gout drug that is still under development.
- The world of natural gout remedies, uric acid's removal can be improved by making it more soluble.
- This is achieved by drinking lots of water and by raising body pH levels in various ways.
- This is a systematic presentation on the uses and history of Uric Acid.
- Use it to understand more about Uric Acid and it's functioning.
Has Been Having a Decent Degree of Success<strong>Elimination of gout attacks </strong>In its most recent statement the developing company's most significant remark was that the extension trial group receiving Pegloticase every two weeks, there were only four gout attacks among those who had been administered Pegloticase (8 mg) every fortnight for two months, in subsequent months. And none in this group had a gout attack after five months of Pegloticase treatment, in following months. All were patients who had been through a phase 3 trial. In addition to what we had mentioned in the previous paragraph, much more has to be said about Kidney Stones. If space permits, we will state everything about it. .
<strong>HOW PEGLOTICASE WORKS </strong> What makes Pegloticase a very interesting, and more importantly, a hopeful new gout drug, is the way it works. All drugs used in gout try to cure or alleviate the disease by reducing the body's uric acid (UA) levels. They do this by either inhibiting its production or making it easier to remove.
Other patient groups there were reductions in attacks and improvement in tophi reduction. Tophi are those knobbly shaped, awkward looking, lumps of MSU crystals that often goutezol in malaysia term gout sufferers.
This suggests that progression of the disease may be joint pain and back pain-to-treat cases, and therefore may not cause other medical conditions such as kidney stones heart disease and hypertension. .
Pegloticase's answer to the excess uric acid level problem is to remove it by ingeniously converting uric acid into something else, a substance called Allantoin. Allantoin is more soluble and better excreted than uric acid. The principle comes from the way most animals do it. They do it by converting UA to Allantoin, but this is something humans cannot do naturally. Hence the formulation of Pegloticase. Once you are through reading what is written here on Gout Drugs, have you considered recollecting what has been written and writing them down? This way, you are bound to have a better understanding on Gout Drugs.